Leitender Arzt
Leiter Leber-, Bauchspeicheldrüsen- und Gallenwegschirurgie
Klinik für Viszeral- und Thoraxchirurgie
Funktion
Qualifikationen
Facharzt für Chirurgie
Schwerpunkttitel Viszeralchirurgie VIS FMH
FEBS EBSQ HPB Surgery
Berufliche Tätigkeiten
seit 09/2020
Leitender Arzt
Klinik für Viszeral- und Thoraxchirurgie
Kantonsspital Winterthur
08/2017 – 08/2020
Oberarzt
Klinik für Viszeral- und Thoraxchirurgie
Kantonsspital Winterthur
2015 – 2017
HPB Fellow (Oberarzt-Äquivalent; Hepatico-Pancreato-Biliäre Chirurgie)
Abteilung für Viszeral- und Transplantationschirurgie
Universitätsspital Zürich
2014 – 2015
Stellvertretender Oberarzt
Abteilung für Viszeral- und Transplantationschirurgie
Universitätsspital Zürich
2013 – 2014
Assistenzarzt
Klinik für Viszeral- und Thoraxchirurgie
Kantonsspital Winterthur
2011 – 2013
Assistenzarzt
Abteilung für Viszeral- und Transplantationschirurgie
Universitätsspital Zürich
2010 – 2011
Locum Chirurg
MEDACS (Senior House Officer)
Whipps Cross, Royal London, Queens, Queen Mary’s, St. Helier und
Watford General Hospital, London, Grossbritannien
2005 – 2008
Assistenzarzt
Abteilung für Allgemein-, Viszeral- und Transplantationschirurgie
Universitätsklinikum Ulm, Deutschland
2005 – 2005
Assistenzarzt
Chirurgische Klinik und Poliklinik
Universität Erlangen, Deutschland
Berufliche Qualifikationen
2019
Schwerpunkttitel Viszeralchirurgie VIS FMH
2018
European Board of Surgery Qualification in Hepatico-Pancreato-Biliärer Chirurgie (EBSQ HPB Surgery)
2014
Facharztprüfung Chirurgie (FMH Schweiz)
2005
Approbation Humanmedizin
Johann Wolfgang Goethe Universität, Frankfurt am Main, Deutschland
Akademisches Résumé
seit 05/2017
Visiting Scholar, Institute for Regenerative Medicine (IREM)
Universität Zürich, Schweiz
2017
Habilitation (Priv. Dozent, PD)
Universität Zürich, Schweiz
2017
Graduierung, Cancer Biology and Therapeutics Program
Harvard Medical School, Boston, USA
2011
Doctor of Philosophy (PhD)
University of Oxford, Grossbritannien
2005
Promotion (Dr. med.)
Orthopädische Universitätsklinik
Frankfurt am Main, Deutschland
Preise und Grants
2018
- Preis für beste orale Präsentation der Association for Research in Surgery (ARS) 106. Jahreskongress der Schweizer Gesellschaft für Chirurgie (SGC), Basel, Schweiz
- Preis für bestes chirurgisches Abstract; Jahreskongress der Schweizer Gesellschaft für Viszeralchirurgie (SGVC), Interlaken, Schweiz
2017
- Grant der Commission for Technology and Innovation (CTI), Schweiz
- Wissenschaftlicher Grant der Science Foundation for Oncology, Schweiz
2016
- Wissenschaftlicher Grant der EMDO Stiftung, Schweiz
- Preis für beste e-Poster Präsentation; 12th World Congress of the International Hepato-Pancreato-Biliary Association (IHPBA) in Sao Paulo, Brasilien
2015
- Wissenschaftlicher Grant der Stiftung Krebsforschung Schweiz
2008 – 2011
- PhD Stipendium des Ludwig Institute for Cancer Research, Univerity of Oxford, Grossbritannien
- A comparison of robotassisted Single-Site and laparoscopic single-incision cholecystectomy for benign gallbladder disease: The results of a randomized controlled trial.
Grochola LF*, Soll C*, Zehnder A, Wyss R, Herzog P, Breitenstein S.
Surgical Endoscopy. In press. IF 3.747 (2016) - A comparison of robotassisted Single-Site and laparoscopic single-incision cholecystectomy for benign gallbladder disease: A protocol for a randomized controlled trial.
Grochola LF*, Soll C*, Zehnder A, Wyss R, Herzog P, Breitenstein S.
BMC SURGERY. 2017 Feb 9;17(1). IF 1.422 (2016) - CD44 SNPrs187115: A novel biomarker signature that predicts survival in resectable pancreatic ductal adenocarcinoma.
Stracquadanio G, Vrugt B, Flury R, Schraml P, Würl P, Müller TH, Knippschild U, Henne-Bruns D, Breitenstein S, Clavien PA, Graf R, Bond GL, Grochola LF.
CLINICAL CANCER RESEARCH. 2016 Dec 15;22(24):6069-6077. IF 10.199 (2017) - LF. MDM2 SNP 309 G allele is associated with younger age at surgery in chronic pancreatitis patients.
Udelnow A, Henne-Bruns D, Knippschild U, Halangk W, Bruns C, Halloul Z, Würl P, Grochola
PANCREAS. 2016 Apr;45(4):e11-2. IF 2.958 (2017) - Prediction of outcome in multiorgan resections for cancer using a bayes-network.
Udelnow A, Leinung S, Grochola LF, Henne-Bruns D, Wuerl P.
HEPATOGASTROENTEROLOGY. 2013; Jun;60(125):1009-13. IF 0.792 (2015) - Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.
Lenos K, Grawenda AM, Lodder K, Kuijjer ML, Teunisse AF, Repapi E, Grochola LF, Bartel F, Hogendoorn PC, Wuerl P, Taubert H, Cleton-Jansen AM, Bond GL, Jochemsen AG.
CANCER RESEARCH. 2012 Aug 15;72(16):4074-84. IF 9.130 (2017) - RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.
Yee KS, Grochola L, Hamilton G, Grawenda A, Bond EE, Taubert H, Würl P, Bond GL, O’Neill EA.
CANCER RESEARCH. 2012 May 1;72(9):2206-17. IF 9.130 (2017) - Expression of microRNA 210 associates with poor survival and age of tumor onset of soft-tissue sarcoma patients.
Greither T, Würl P, Grochola LF, Bond GL, Bache M, Kappler M, Lautenschläger C, Holzhausen HJ, Wach S, Eckert A, Taubert H.
INT J CANCER. 2012 Mar 1;130(5):1230-5. IF 6.513 (2016) - Elevated transcript levels from the MDM2 P1 promoter and low p53 transcript levels are associated with poor prognosis in human pancreatic ductal adenocarcinoma.
Grochola LF, Taubert H, Greither T, Bhanot U, Udelnow A, Würl P.
PANCREAS. 2011; 40(2):265-70. IF 2.958 (2017) - A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence.
Vazquez A, Kulkarni D, Grochola LF, Bond GL, Barnard N, Toppmeyer D, Levine AJ, Hirshfield KM.
INT J CANCER. 2011 May 15;128(10):2335-43. IF 6.513 (2016) - An analysis of cellular responses to chemotherapeutics identifies human genetic variants in YWHAQ (14-3-3 tau) and CD44 that affect sarcoma incidence and survival.
Vazquez A*, Grochola LF*, Bond EE, Levine AJ, Taubert H, Müller TH, Würl P, Bond GL.
CANCER RESEARCH. 2010; 70(1):172-80. IF 9.130 (2017) - Single Nucleotide Polymorphisms in the p53 Signaling Pathway.
Grochola LF, Zeron-Medina J, Mériaux S, Bond GL.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2010; 2(5):a001032. IF 11.224 (2017) - Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival.
Greither T, Grochola LF, Udelnow A, Lautenschlager C, Würl P, Taubert H.
INT J CANCER. 2010; 126(1):73-80. IF 6.513 (2016) - MDM2 SNP309 Associates With Accelerated Pancreatic Adenocarcinoma Formation.
Grochola LF, Muller TH, Bond GL, Taubert H, Udelnow A, Würl P.
PANCREAS. 2010; 39(1):76-80. IF 2.958 (2017) - Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival.
Grochola LF*, Vazquez A*, Bond EE, Levine AJ, Taubert H, Müller TH, Würl P, Bond GL.
CLINICAL CANCER RESEARCH. 2009; 15:6301-8. IF 10.199 (2017) - The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death.
Grochola LF, Greither T, Taubert H, Moller P, Knippschild U, Udelnow A, Henne-Bruns D, Würl P.
BR J CANCER. 2008; 99:1083-8. IF 6.176 (2016) - Interleukin-13 exerts autocrine growth-promoting effects on human pancreatic cancer, and its expression correlates with a propensity for lymph node metastases.
Formentini A, Prokopchuk O, Sträter J, Kleeff J, Grochola LF, Leder G, Henne-Bruns D, Korc M, Kornmann M.
INT J COLORECTAL DIS. 2009; 24:57-67. IF 2.383 (2015) - Prognostic relevance of hTERT mRNA expression in ductal adenocarcinoma of the pancreas.
Grochola LF, Greither T, Taubert HW, Moller P, Knippschild U, Udelnow A, Henne-Bruns D, Würl P.
NEOPLASIA. 2008; 10:973-6. IF 4.509 (2015) - Comparison of periprosthetic bone remodelling after implantation of anatomic and straight stem prostheses in total hip arthroplasty.
Grochola LF, Habermann B, Mastrodomenico N, Kurth A.
ARCH ORTHOP TRAUMA SURG. 2008; 128:383-92. IF 1.496 (2015)
* geteilte Erstautorenschaft
BUCHKAPITEL
- Grochola LF, Petrowsky H, Clavien PA: Benign Hepatic Neoplasms; Yeo CJ (Ed): 8th Edition of Shackelford’s Surgery of the Alimentary Tract. Elsevier. 2017
- Busuttil R, Grochola LF, Petrowsky H: Liver Transplantation; Fisher JE, Jones DB, Pomposelli FB, Upchurch R (Eds): Fisher´s Mastery of Surgery (7th Edition). Wolters Kluwer. 2017.
- Grochola LF, Vonlanthen R. Surgical Devices: Haemostasis, Sealing and Dissection; Clavien PA; Sarr MG, Fong Y (Eds): 2nd Edition of the Atlas of Upper Gastrointestinal and Hepato-Pancreato-Biliary Surgery. Springer. 2015
- Grochola LF, Zeron-Medina J, Repapi E, Finlayson AE, Cai Y, Atwal GS, Bond GL: The Inheritance of p53; Hainaut PO, Magali W, Klas G (Eds): p53 in the clinics. Springer. 2013.
- Grochola LF, Zeron-Medina J, Mériaux S, Bond GL: Single Nucleotide Polymorphisms in the p53 Signaling Pathway; Levine A, Lane D (Eds): The p53 family. Cold Spring Harbor Perspectives in Biology. 2010